However, they could eat as much as they wished at other meals or have snacks.
For the final two weeks, the other half of the volunteers followed the same portion-controlled plan.
The scientists found that over the 10 days of consuming a portion-controlled lunch, the 17 participants had 250 fewer calories per day than usual and lost, on average, 1.1 pounds.
"The results confirm that humans do not regulate energy intake with any precision. Over a year, such a regiment would result in losing at least 25 pounds," The Daily Mail quoted Prof Levitsky as saying.
The study suggests that both high-protein and high-fibre meal replacements result in weight loss not by suppressing appetite, but by providing fewer calories.
As humans do not possess accurate mechanisms to compensate for the smaller intake at a previous meal, they end up taking in fewer calories.
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